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Signal Transduction Metabolism Plasma Membrane ATPases

Erythromycin, Macrolide antibiotic (ab141205)

Price and availability

50 256 ₸

Availability

Order now and get it on Friday March 05, 2021

Key features and details

  • Macrolide antibiotic
  • CAS Number: 114-07-8
  • Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Erythromycin, Macrolide antibiotic
  • Description

    Macrolide antibiotic
  • Biological description

    Macrolide antibiotic. Inhibits cytochrome p450 3A4 and P-glycoprotein. Binds the 50S ribosomal subunit and inhibits protein synthesis in Gram-positive and Gram-negative bacteria.

  • CAS Number

    114-07-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6- {[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}- 14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)- 5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}- 3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione (for erythromycin A)
  • Molecular weight

    733.94
  • Molecular formula

    C37H67NO13
  • PubChem identifier

    16212992
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(C)[C@H]3C[C@@H](C)O[C@@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)[C@@H]3O
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Metabolism
    • Plasma Membrane
    • ATPases
    • Microbiology
    • Antimicrobial
    • Antibiotic
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Chemical Type
    • Antibiotic
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Cytochrome P450
    • Inhibitors
    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Cytochromes
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Transporters
    • ABC transporter
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • Protein synthesis
    • Biochemicals
    • Research Area
    • Cancer
    • DNA, RNA & protein synthesis
    • Protein synthesis
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Antibacterial

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