(E)-2,3',4,5'-Tetramethoxystilbene, CYP1B1 inhibitor (ab141095)
Key features and details
- Potent, selective CYP1B1 inhibitor
- CAS Number: 24144-92-1
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(E)-2,3',4,5'-Tetramethoxystilbene, CYP1B1 inhibitor -
Description
Potent, selective CYP1B1 inhibitor -
Biological description
Potent, selective CYP1B1 inhibitor (IC50 values are 6, 300 and 3100 nM for 1B1, 1A1 and 1A2, respectively). Competitive inhibitor (Ki = 3 nM). Anticancer activity in vitro.
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Purity
> 98% -
CAS Number
24144-92-1 -
Chemical structure
Properties
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Chemical name
1-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]-2,4-dimethoxybenzene -
Molecular weight
300.35 -
Molecular formula
C18H20O4 -
PubChem identifier
5354004 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COc2cc(ccc2/C=C/c1cc(OC)cc(OC)c1)OC -
Source
Synthetic
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Research areas
