DMPQ dihydrochloride, PDGFRbeta inhibitor (ab141269)
Key features and details
- Potent and selective PDGFRβ inhibitor
- CAS Number: 1123491-15-5
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
DMPQ dihydrochloride, PDGFRbeta inhibitor -
Description
Potent and selective PDGFRβ inhibitor -
Biological description
Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.
Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration. -
Purity
> 99% -
CAS Number
1123491-15-5 -
Chemical structure
Properties
-
Chemical name
5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride -
Molecular weight
339.22 -
Molecular formula
C16H14N2O2.2HCl -
PubChem identifier
45073427 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
Cl.Cl.COc1cc(OC)nc2ccc(cc12)c3ccncc3 -
Source
Synthetic
-
Research areas
