(-)-Deguelin, Akt inhibitor (ab120941)
Key features and details
- Akt inhibitor. Anticancer agent.
- CAS Number: 522-17-8
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(-)-Deguelin, Akt inhibitor -
Description
Akt inhibitor. Anticancer agent. -
Alternative names
- (-)-cis-Deguelin
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Biological description
Akt inhibitor. Anticancer agent. Inhibits cell growth (IC50 = 43.2 nM) in vitro. Anticancer and antiangiogenic activities in vivo. -
Purity
> 98% -
CAS Number
522-17-8 -
Chemical structure
Properties
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Chemical name
(7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one -
Molecular weight
394.42 -
Molecular formula
C23H22O6 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COc1cc2c(OC[C@H]3Oc4c(ccc5OC(C)(C)C=Cc45)C(=O)[C@@H]23)cc1OC -
Source
Synthetic
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Research areas
