D-erythro MAPP, alkaline ceramidase inhibitor (ab141754)
Key features and details
- Specific alkaline ceramidase inhibitor
- CAS Number: 143492-38-0
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
D-erythro MAPP, alkaline ceramidase inhibitor -
Description
Specific alkaline ceramidase inhibitor -
Biological description
Specific inhibitor of alkaline ceramidase (IC50 = 1 μM). Elevates endogenous ceramide leading to growth suppression and cell cycle arrest. Inhibits acid ceramidase (IC50 = 500 μM). Cell-permeable. Active in vitro. -
Purity
> 98% -
CAS Number
143492-38-0 -
Chemical structure
Properties
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Chemical name
N-[(1S,2R)-1-Hydroxy-1-phenylpropan-2-yl]tetradecanamide -
Molecular weight
361.60 -
Molecular formula
C23H39NO2 -
PubChem identifier
124735 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCCCCCCCCCC(=O)NC(C)C(C1=CC=CC=C1)O -
Source
Synthetic
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Research areas
