CVT 313, CDK2 inhibitor (ab254327)
Key features and details
- Potent and selective CDK2 inhibitor
- CAS Number: 199986-75-9
- Purity: > 98%
Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CVT 313, CDK2 inhibitor -
Description
Potent and selective CDK2 inhibitor -
Alternative names
- CVT313
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Biological description
Potent and selective CDK2 inhibitor (IC50 ranging between 1.25 µM to 20 µM). Inhibition is competitive with respect to ATP (Ki = 95 nM). Displays >7-fold selectivity for cdk2 and cdk5 over other cdks. Inhibits cdk5 in sub-micromolar range (IC50 = 0.42 μM).
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Purity
> 98% -
General notes
Protect from air and light
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CAS Number
199986-75-9 -
Chemical structure
Properties
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Chemical name
2-[2-Hydroxyethyl-[6-[(4-methoxyphenyl)methylamino]-9-propan-2-ylpurin-2-yl]amino]ethanol
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Molecular weight
400.48 -
Molecular formula
C20H28N6O3 -
PubChem identifier
6918386 -
Storage instructions
Shipped at 4°C. Store at -20°C long term. Store In the Dark. -
Solubility overview
Soluble in DMSO to 25 mM
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=C(C=C3)OC)N(CCO)CCO -
Source
Synthetic
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Research areas
