CNQX disodium salt, AMPA / kainate antagonist (ab120044)
Key features and details
- AMPA / kainate antagonist; water soluble
- CAS Number: 479347-85-8
- Purity: > 99%
- Soluble in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CNQX disodium salt, AMPA / kainate antagonist -
Description
AMPA / kainate antagonist; water soluble -
Biological description
Water soluble, potent, competitive AMPA / kainate receptor antagonist. Also antagonist at NMDA receptor glycine site.
Also available in simple stock solutions (ab144488) - add 1 ml of water to get an exact, ready-to-use concentration. -
Purity
> 99% -
CAS Number
479347-85-8 -
Chemical structure
Images
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Functional Studies - CNQX disodium salt, AMPA / kainate antagonist (ab120044)ab96379 staining MEK1 (phospho S298) in SK-N-SH cells treated with CNQX disodium salt (ab120044), by ICC/IF. Decrease in MEK1 (phospho S298) expression correlates with increased concentration of CNQX disodium salt, as described in literature.
The cells were incubated at 37°C for 24h in media containing different concentrations of ab120044 (CNQX disodium salt) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab96379 (1/100 dilution) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.