CldU (5-chloro-2'-deoxyuridine), Halogenated uridine derivative (ab213715)
Key features and details
- Halogenated uridine derivative
- CAS Number: 50-90-8
Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CldU (5-chloro-2'-deoxyuridine), Halogenated uridine derivative -
Description
Halogenated uridine derivative -
Alternative names
- 2’-Deoxy-5-chlorouridine
- 5-Chlorodeoxyuridine
- 5-CldU
- Chlorodeoxyuridine
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Biological description
Thymidine analogue, readily incorporated following phosphorylation, into newly synthesized DNA in place of thymidine. Used to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors.
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CAS Number
50-90-8 -
Chemical structure
Properties
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Chemical name
5-Chloro-2'-deoxyuridine
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Molecular weight
262.65 -
Molecular formula
C9H11ClN2O5 -
PubChem identifier
65510 -
Storage instructions
Store at -20°C. -
Solubility overview
Soluble in water
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)Cl)CO)O -
Source
Synthetic