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cis-ACBD (1-Aminocyclobutane-1,3-dicarboxylic acid), L-glutamate uptake inhibitor (ab146128)

Key features and details

  • Selective, competitive L-glutamate uptake inhibitor
  • CAS Number: 73550-55-7
  • Soluble in 1eq. NaOH to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    cis-ACBD (1-Aminocyclobutane-1,3-dicarboxylic acid), L-glutamate uptake inhibitor
  • Description

    Selective, competitive L-glutamate uptake inhibitor
  • Biological description

    Selective, competitive L-glutamate uptake inhibitor (IC50 = 30 μM). Increases basal and potassium evoked D-aspartate release.

  • CAS Number

    73550-55-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    cis-1-Amino-1,3-cyclobutanedicarboxylic acid
  • Molecular weight

    159.14
  • Molecular formula

    C6H9NO4
  • PubChem identifier

    1214
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in 1eq. NaOH to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1C(CC1(C(=O)O)N)C(=O)O
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Glutamate Receptors
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Ligand-Gated Ion Channels
    • NMDA Receptors
    • Signal Transduction
    • Growth Factors/Hormones
    • Hormones
    • Neuroscience
    • Sensory System
    • Somatosensory system
    • Nociception
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Other
    • Cancer
    • Tumor biomarkers
    • Other
    • Cardiovascular
    • Atherosclerosis
    • Lipoprotein metabolism
    • Cardiovascular
    • Lipids / Lipoproteins
    • Fatty Acids
    • Metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipoprotein metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Fatty acids
    • Metabolism
    • Types of disease
    • Heart disease
    • Metabolism
    • Pathways and Processes
    • Redox metabolism
    • Fatty acid oxidation

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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