Cilastatin Sodium, dehydrodipeptidase I inhibitor (ab144544)
Key features and details
- Selective dehydrodipeptidase I inhibitor
- CAS Number: 81129-83-1
- Purity: > 98%
- Soluble in water to 50 mM and in DMSO to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cilastatin Sodium, dehydrodipeptidase I inhibitor -
Description
Selective dehydrodipeptidase I inhibitor -
Biological description
Selective dehydrodipeptidase I inhibitor (Ki = 0.11 µM). Inhibits leukotriene D4 hydrolase (Ki = 0.11 µM). Potentiates the antibiotic activity of Imipenem (ab141030). Shows nephroprotective effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
81129-83-1 -
Chemical structure
Properties
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Chemical name
(Z)-7-[(2R)-2-Amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoate sodium -
Molecular weight
380.43 -
Molecular formula
C16H25N2NaO5S -
PubChem identifier
23663403 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 50 mM and in DMSO to 25 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1(C[C@@H]1C(=O)N/C(=C\CCCCSC[C@@H](C(=O)O)N)/C(=O)[O-])C.[Na+] -
Source
Synthetic
