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CHS-828, NF-kappabeta inhibitor (ab142208)

Key features and details

  • NF-κβ inhibitor. Potent antineoplastic agent
  • CAS Number: 200484-11-3
  • Purity: > 98%
  • Soluble in DMSO and in ethanol
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    CHS-828, NF-kappabeta inhibitor
  • Description

    NF-κβ inhibitor. Potent antineoplastic agent
  • Biological description

    NF-κβ inhibitor. Potent antineoplastic agent. Shows antitumor effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    200484-11-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine
  • Molecular weight

    371.86
  • Molecular formula

    C19H22ClN5O
  • PubChem identifier

    148198
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC(=CC=C1OCCCCCCN=C(NC#N)NC2=CC=NC=C2)Cl
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cytochromes
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Cytokines, NF-κB & IκB signaling
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipases
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Drug metabolism
    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Cytochromes

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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