CGP 37157, Na+-Ca2+ exchange inhibitor (ab120012)
Key features and details
- Na+-Ca2+ exchange inhibitor
- CAS Number: 75450-34-9
- Purity: > 99%
- Soluble in water to 5 mM, in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CGP 37157, Na+-Ca2+ exchange inhibitor -
Description
Na+-Ca2+ exchange inhibitor -
Biological description
Selective inhibitor of the mitochondrial Na+-Ca2+ exchanger (IC50 = 0.4 μM).
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Purity
> 99% -
CAS Number
75450-34-9 -
Chemical structure
Properties
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Chemical name
7-Chloro-5-(2-chlorophenyl)-1,2,3,5-tetrahydro-4,1-benzothiazepin-2-one -
Molecular weight
324.22 -
Molecular formula
C15H11Cl2NOS -
PubChem identifier
2688 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM, in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Clc3ccccc3C1SCC(=O)Nc2ccc(Cl)cc12 -
Source
Synthetic
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Research areas