CDDO imidazolide, Fatty acid synthesis inhibitor (ab143794)
Key features and details
- Fatty acid synthesis inhibitor.
- CAS Number: 443104-02-7
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CDDO imidazolide, Fatty acid synthesis inhibitor -
Description
Fatty acid synthesis inhibitor. -
Alternative names
- 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole
- 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide
- CDDO-Im
see all -
Biological description
Synthetic triterpenoid. Inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers. Potent inducer of Heme Oxygenase-1 and Nrf2/ARE Signaling.
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CAS Number
443104-02-7 -
Chemical structure
Properties
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Chemical name
1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole -
Molecular weight
541.72 -
Molecular formula
C34H43N3O3 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic