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CDDO imidazolide, Fatty acid synthesis inhibitor (ab143794)

Key features and details

  • Fatty acid synthesis inhibitor.
  • CAS Number: 443104-02-7
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    CDDO imidazolide, Fatty acid synthesis inhibitor
  • Description

    Fatty acid synthesis inhibitor.
  • Alternative names

    • 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole
    • 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide
    • CDDO-Im
    • RTA 403
    • TP 235
    see all
  • Biological description

    Synthetic triterpenoid. Inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers. Potent inducer of Heme Oxygenase-1 and Nrf2/ARE Signaling.

  • CAS Number

    443104-02-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole
  • Molecular weight

    541.72
  • Molecular formula

    C34H43N3O3
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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