CAY 10566, SCD1 inhibitor (ab144421)
Key features and details
- Potent, selective SCD1 inhibitor
- CAS Number: 944808-88-2
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CAY 10566, SCD1 inhibitor -
Description
Potent, selective SCD1 inhibitor -
Biological description
Potent, selective SCD1 inhibitor (IC50 values are 4.5 and 26 nM in mouse and human SCD1, respectively). Inhibits saturated, long-chain fatty acyl-CoAs conversion to monounsaturated, long-chain fatty acyl-CoAs (IC50 values are 7.9 and 6.8 nM for heptadecanoic acid and palmitic acid, respectively).
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Purity
> 99% -
CAS Number
944808-88-2 -
Chemical structure
Properties
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Chemical name
3-[4-(2-Chloro-5-fluorophenoxy)-1-piperidinyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)pyridazine -
Molecular weight
389.82 -
Molecular formula
C18H17ClFN5O2 -
PubChem identifier
16732433 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=NN=C(O1)C2=NN=C(C=C2)N3CCC(CC3)OC4=C(C=CC(=C4)F)Cl -
Source
Synthetic
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Research areas
