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BTS, Ca2+-stimulated myosin S1 ATPase (ab145875)

Key features and details

  • Selective inhibitor of Ca2+-stimulated myosin S1 ATPase
  • CAS Number: 1576-37-0
  • Purity: > 95%
  • Soluble in DMSO
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    BTS, Ca2+-stimulated myosin S1 ATPase
  • Description

    Selective inhibitor of Ca2+-stimulated myosin S1 ATPase
  • Alternative names

    • 4-Methyl-N-(phenylmethyl)benzenesulfonamide
    • Battenin
    • CLN3
    • N-Benzyl-4-methylbenzenesulfonamide
    • N-Benzyl-p-toluenesulphonamide
    • NSC 37123
    see all
  • Biological description

    Selective inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 = ~5 µM). Reversibly blocks the gliding motility and weakens myosin’s interaction with F-actin. Much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.

  • Purity

    > 95%
  • CAS Number

    1576-37-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-Benzyl-p-toluenesulphonamide
  • Molecular weight

    261.30
  • Molecular formula

    C14H15NO2S
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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