BML-288, PDE2 inhibitor (ab146167)
Key features and details
- PDE2 inhibitor
- CAS Number: 851681-89-5
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BML-288, PDE2 inhibitor -
Description
PDE2 inhibitor -
Alternative names
- 5-Methyl-6-oxo-N-(1,3,4-thiadiazol-2-yl)-7H-furo[2,3-f]indole-7-carboxamide
- BML288
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Biological description
Potent, selective phosphodiesterase Type II (PDE2) inhibitor (IC50 = 40 nM). Demonstrates no inhibition of 5-lipoxygenase (5-LO) or cyclooxygenase (COX-1).
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CAS Number
851681-89-5 -
Chemical structure
Properties
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Molecular weight
314.32 -
Molecular formula
C14H10N4O3S -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(C2c1cc3occc3cc1N(C)C2=O)Nc4nncs4 -
Source
Synthetic