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Signal Transduction Protein Phosphorylation Ser / Thr Phosphatases

BML-267, protein tyrosine phosphatase 1B (PTP1B) inhibitor (ab141734)

Key features and details

  • Selective protein tyrosine phosphatase 1B (PTP1B) inhibitor
  • CAS Number:
  • Purity: > 95%
  • Soluble in DMSO to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    BML-267, protein tyrosine phosphatase 1B (PTP1B) inhibitor
  • Description

    Selective protein tyrosine phosphatase 1B (PTP1B) inhibitor
  • Biological description

    Selective protein tyrosine phosphatase 1B (PTP1B) inhibitor (IC50 = 11 μM). Enhances leptin-induced STAT3 activation in vitro.
  • Purity

    > 95%
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-Methyl-2-(oxalylamino)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid trifluoroacetic acid salt
  • Molecular weight

    398.30
  • Molecular formula

    C11H12N2O5S.C2HF3O2
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    FC(F)(F)C(=O)O.O=C(O)C(=O)Nc2sc1CN(C)CCc1c2C(=O)O
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Phosphatases
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Phosphatase
    • Protein tyrosine phosphatase

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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