Biotin Anti-MRP8 + MRP14 antibody (ab51863)
Key features and details
- Biotin Chicken polyclonal to MRP8 + MRP14
- Suitable for: IHC-P
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgY
Overview
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Product name
Biotin Anti-MRP8 + MRP14 antibody
See all MRP8 + MRP14 primary antibodies -
Description
Biotin Chicken polyclonal to MRP8 + MRP14 -
Host species
Chicken -
Conjugation
Biotin -
Specificity
Does not discriminate between the individual subunits MRP8 or MRP14. -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P Human
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Immunogen
Recombinant MRP8/14 heterocomplex (Human). The antigen is produced by the Ca2+ dependent heterocomplex formation of MRP8 (S100A8 or Calgranulin A) and MRP14 (S100A9 or Calgranulin B), two calcium binding proteins of the S 100 protein family.
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Positive control
- Human tonsil.
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General notes
Peripheral blood monocytes carry the antigen extra and intracellularly, neutrophils only intracellularly. The antigen is present on macrophages in the red pulp of the spleen and in the liver. It is also strongly expressed on macrophages in acute inflamed tissues (peridontitis, contact excema, urticaria, erythrodermia).In immune histochemistry, this antibody detects early inflammatory macrophages and can thus be used for the classification of acute stage inflammation in tissue sections and in smears.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20 -
Concentration information loading... -
Purity
IgY fraction -
Purification notes
Purified from egg yolk by repeated precipitation. -
Primary antibody notes
In immune histochemistry, this antibody detects early inflammatory macrophages and can thus be used for the classification of acute stage inflammation in tissue sections and in smears. -
Clonality
Polyclonal -
Isotype
IgY -
Research areas
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Biotin Anti-MRP8 + MRP14 antibody (ab51863)ab51863 at 4µg/ml staining human spleen; paraffin embedded.
