Bicalutamide (ICI176334), Androgen receptor antagonist (ab141249)
Key features and details
- Non-steroidal, competitive androgen receptor antagonist
- CAS Number: 90357-06-5
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Bicalutamide (ICI176334), Androgen receptor antagonist -
Description
Non-steroidal, competitive androgen receptor antagonist -
Alternative names
- ICI176334
-
Biological description
Non-steroidal, competitive androgen receptor antagonist (IC50 = 190 nM). Displays anticancer activity. Active in vivo.
-
Purity
> 99% -
CAS Number
90357-06-5 -
Chemical structure
Properties
-
Chemical name
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide -
Molecular weight
430.37 -
Molecular formula
C18H14F4N2O4S -
PubChem identifier
2375 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
Fc1ccc(cc1)S(=O)(=O)CC(C)(O)C(=O)Nc2cc(c(C#N)cc2)C(F)(F)F -
Source
Synthetic
-
Research areas
