beta-Nicotinamide mononucleotide, Key NAD+ intermediate (ab223879)
Key features and details
- Key NAD+ intermediate
- CAS Number: 1094-61-7
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
beta-Nicotinamide mononucleotide, Key NAD+ intermediate -
Description
Key NAD+ intermediate -
Alternative names
- Nicotinamide ribotide
- NMN
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Biological description
Product of the NAMPT reaction and a key intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Ameliorates glucose intolerance by restoring NAD+ levels in high-fat diet (HFD)-induced T2D mice. Enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
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Purity
> 98% -
General notes
Protect from air and moisture.
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CAS Number
1094-61-7 -
Chemical structure
Properties
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Chemical name
Nicotinamide-1-ium-1-β-D-ribofuranoside 5'-phosphate -
Molecular weight
334.22 -
Molecular formula
C11H15N2O8P -
PubChem identifier
14180 -
Storage instructions
Shipped at 4°C. Store at -20°C long term. Store under desiccating conditions. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)[O-])O)O)C(=O)N -
Source
Synthetic
