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Epigenetics and Nuclear Signaling Transcription Domain Families Zinc Finger

Benzo[a]pyrene (B[a]P), Mutagenic agent (ab142566)

Key features and details

  • Mutagenic agent
  • CAS Number: 50-32-8
  • Purity: > 98%
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Benzo[a]pyrene (B[a]P), Mutagenic agent
  • Description

    Mutagenic agent
  • Alternative names

    • B[a]P
  • Biological description

    Mutagenic agent. Inhibits EROD activtiy (IC50 values are 31, 140 and 350 nM at P450 1B1, 1A2 and 1A1 respectively). Causes DNA adducts in vivo. Upregulates the expression of HPV E7oncoprotein. Orally active.
  • Purity

    > 98%
  • CAS Number

    50-32-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Benzo[a]pyrene
  • Molecular weight

    252.32
  • Molecular formula

    C20H12
  • PubChem identifier

    2336
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C2C3=C4C(=CC2=C1)C=CC5=C4C(=CC=C5)C=C3
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • HLH / Leucine Zipper
    • Helix-Turn-Helix
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Estrogen
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Testosterone
    • Neuroscience
    • Endocrine system
    • Gonadotrophic axis
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Estrogen
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Testosterone
    • Cancer
    • Signal transduction
    • Nuclear signaling
    • Nuclear hormone receptors
    • Estrogen
    • Cancer
    • Signal transduction
    • Nuclear signaling
    • Nuclear hormone receptors
    • Other
    • Cancer
    • Tumor biomarkers
    • Receptors
    • Developmental Biology
    • Reproduction
    • Hormones
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • DNA & RNA synthesis

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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