B02, RAD51 recombinase inhibitor (ab254543)
Key features and details
- RAD51 recombinase inhibitor
- CAS Number: 1290541-46-6
Soluble in DMSO to 100 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
B02, RAD51 recombinase inhibitor -
Description
RAD51 recombinase inhibitor -
Biological description
RAD51 recombinase inhibitor (IC50 = 27.4 μM). Selective over E.coli RecA homolog (IC50 >250 μM). Inhibits homologous recombination. Increases sensitivity of cells to DNA damage. Increases sensitivity of cancer cells to DNA-damaging chemotherapeutics.
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CAS Number
1290541-46-6 -
Chemical structure
Properties
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Chemical name
3-Benzyl-2-[(E)-2-pyridin-3-ylethenyl]quinazolin-4-one
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Molecular weight
339.40 -
Molecular formula
C22H17N3O -
PubChem identifier
5738263 -
Storage instructions
Shipped at Room Temperature. Store at +4°C. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 10 mM
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Handling
Toxic, refer to SDS for further information.
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SMILES
C1=CC=C(C=C1)CN2C(=NC3=CC=CC=C3C2=O)/C=C/C4=CN=CC=C4 -
Source
Synthetic
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Research areas
