Azithromycin dihydrate, Macrolide antibiotic (ab141064)
Key features and details
- Macrolide antibiotic
- CAS Number: 117772-70-0
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Azithromycin dihydrate, Macrolide antibiotic -
Description
Macrolide antibiotic -
Biological description
Macrolide antibiotic. Bacterial 50S ribosomal inhibitor. Inhibits translation, cell viability and growth rate of bacterial cells (IC50 = 0.4 μg/ml). Orally active against gram-negative and gram-positive bacteria.
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CAS Number
117772-70-0 -
Chemical structure
Properties
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Chemical name
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one -
Molecular weight
785.02 -
Molecular formula
C38H72N2O12.2H2O -
PubChem identifier
447043 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)[C@H]3C[C@@H](C)O[C@@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@]2(C)O)[C@@H]3O -
Source
Synthetic
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Research areas