AS-252424, PI3Kgamma inhibitor (ab120929)
Key features and details
- Potent and selective PI3Kγ inhibitor
- CAS Number: 900515-16-4
- Purity: > 95%
- Soluble in DMSO to 50 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
AS-252424, PI3Kgamma inhibitor -
Description
Potent and selective PI3Kγ inhibitor -
Biological description
Potent, selective and ATP-competitive PI3Kγ inhibitor (IC50 values are 33 nM (PI3Kγ), 935 nM (PI3Kα) and 20 μM (PI3Kβ and PI3Kδ)). Active in vivo. -
Purity
> 95% -
CAS Number
900515-16-4 -
Chemical structure
Properties
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Chemical name
5-[5-(4-Fluoro-2-hydroxyphenyl)furan-2-ylmethylene]-2,4-thiazolidinedione -
Molecular weight
305.28 -
Molecular formula
C14H8FNO4S -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(N([H])C(S/1)=O)C1=CC2=CC=C(C3=C(O)C=C(F)C=C3)O2 -
Source
Synthetic
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Research areas
