Anti-TRAIL antibody [2E5] (ab2219)
![Anti-TRAIL antibody [2E5] (ab2219)](https://www.abcam.com/ps/products/2/ab2219/Images/ab2219-5477-anti-trail-antibody-2e5.jpg "Anti-TRAIL antibody [2E5] (ab2219)")
Key features and details
- Mouse monoclonal [2E5] to TRAIL
- Suitable for: Functional Studies
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-TRAIL antibody [2E5]
See all TRAIL primary antibodies -
Description
Mouse monoclonal [2E5] to TRAIL -
Host species
Mouse -
Specificity
This antibody is specific for TRAIL, Tumour necrosis factor (TNF) related apoptosis inducing ligand (TRAIL/ APO2-L)).
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Tested applications
Suitable for: Functional Studiesmore details -
Species reactivity
Reacts with: Human
Does not react with: Mouse -
Immunogen
Recombinant soluble fragment, corresponding to amino acids 95-281 of Human TRAIL.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Constituent: PBS -
Concentration information loading... -
Purity
Protein A purified -
Purification notes
Purified from TCS. -
Clonality
Monoclonal -
Clone number
2E5 -
Myeloma
unknown -
Isotype
IgG1 -
Light chain type
unknown -
Research areas
Images
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Functional Studies - Anti-TRAIL antibody [2E5] (ab2219)Apoptosis induced in JURKAT human T cell leukemia cell line by soluble recombinant human TRAIL is completely blocked by anti-human TRAIL (2E5).
The neutralizing activity of the antibody 2E5 has been confirmed with various sources of soluble recombinant human TRAIL.
A - medium
B - recombinant TRAIL
C - recombinant TRAIL + anti-human TRAIL (2E5; 0.06 µg/ml)
D - recombinant TRAIL + anti-human TRAIL (2E5; 0.24 µg/ml)
E - recombinant TRAIL + Isotype mouse IgG1 control
