Antibodies, Proteins, Kits and Reagents for Life Science

274 732 ₸ Product size

100 µg 274 732 ₸

Order now and get it on Thursday February 25, 2021

Key features and details

Product name

Anti-Tbx6 antibody
See all Tbx6 primary antibodies
Description

Rabbit polyclonal to Tbx6
Host species

Rabbit
Tested Applications & Species

Application Species
WB
Mouse

See all applications and species data
Immunogen

Synthetic peptide corresponding to Mouse Tbx6 aa 1-100 conjugated to keyhole limpet haemocyanin.
(Peptide available as ab26243)

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS

Batches of this product that have a concentration
Concentration information loading...
Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab38883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application	Species
WB	Mouse

Application	Abreviews	Notes
WB	(1)	Use a concentration of 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 59 kDa).

Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 59 kDa).

Function

Probable transcriptional regulator involved in developmental processes. Could be required for specification of paraxial mesoderm structures during gastrulation.
Tissue specificity

Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.
Sequence similarities

Contains 1 T-box DNA-binding domain.
Developmental stage

Expressed during gastrulation and during a second phase in some adult tissues.
Cellular localization

Nucleus.
Target information above from: UniProt accession O95947 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 6911 Human
- Entrez Gene: 21389 Mouse
- Omim: 602427 Human
- SwissProt: O95947 Human
- SwissProt: P70327 Mouse
- Unigene: 198301 Human
- Unigene: 727 Mouse
Alternative names
- DFNB 67 antibody
- DFNB67 antibody
- SCDO5 antibody
- T box 6 antibody
- T box protein 6 antibody
- T box transcription factor TBX 6 antibody
- T box transcription factor TBX6 antibody
- T-box protein 6 antibody
- T-box transcription factor TBX6 antibody
- Tbox 6 antibody
- TBX 6 antibody
- tbx6 antibody
- TBX6_HUMAN antibody
see all

Publishing research using ab38883? Please let us know so that we can cite the reference in this datasheet.

ab38883 has been referenced in 4 publications.

Bredenkamp N et al. Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency. Stem Cell Reports 13:1083-1098 (2019). PubMed: 31708477
Liu C et al. Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells. Stem Cell Reports 11:43-57 (2018). PubMed: 30008328
Chal J et al. Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro. Nat Protoc 11:1833-50 (2016). PubMed: 27583644
Gouti M et al. In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PLoS Biol 12:e1001937 (2014). ICC/IF ; Mouse . PubMed: 25157815