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Neuroscience Neurotransmitter Neuropeptides Tachykinins

Anti-Substance P antibody (ab10353)

Price and availability

331 689 ₸

Availability

Order now and get it on Friday July 23, 2021

Anti-Substance P antibody (ab10353)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Guinea pig polyclonal to Substance P
  • Suitable for: IHC-FoFr, ICC/IF
  • Reacts with: Mouse, Rat
  • Isotype: IgG

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Overview

  • Product name

    Anti-Substance P antibody
    See all Substance P primary antibodies
  • Description

    Guinea pig polyclonal to Substance P
  • Host species

    Guinea pig
  • Tested applications

    Suitable for: IHC-FoFr, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    CRPKPQQFFGLM

    , corresponding to amino acids 1-11 of Rat Substance P (Peptide available as ab38217.)
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • General notes


    This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Alternative splicing of exons 4 and/or 6 produces four known products of undetermined significance.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituent: Whole serum
  • Concentration information loading...
  • Purity

    Whole antiserum
  • Primary antibody notes

    This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Alternative splicing of exons 4 and/or 6 produces four known products of undetermined significance.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Neuropeptides
    • Tachykinins
    • Neuroscience
    • Neurotransmitter
    • Neuropeptides
    • Hormones
    • Neuroscience
    • Sensory System
    • Somatosensory system
    • Nociception
    • Neuroscience
    • Neurology process
    • Metabolism
    • Metabolism
    • Types of disease
    • Cancer

Images

  • Immunocytochemistry/ Immunofluorescence - Anti-Substance P antibody (ab10353)
    Immunocytochemistry/ Immunofluorescence - Anti-Substance P antibody (ab10353)
    Immuofluorescent detection of Substance P in rat spinal cord dorsal horn (red fluorescence). DAPI (blue) was used as counter stain.
  • Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Substance P antibody (ab10353)
    Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Substance P antibody (ab10353) Image from Jeffry JA et al., PLoS One. 2009 Sep 15;4(9):e7021. doi: 10.1371/journal.pone.0007021. Fig 6.; September 15, 2009, PLoS ONE 4(9): e7021.
    Immunohistochemical analysis of rat paw skin tissue, staining Substance P with ab10353 at 1/1000 dilution.
  • Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Substance P antibody (ab10353)
    Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Substance P antibody (ab10353)
    ab10353 staining Substance P in mouse spinal cord (red fluorescence) by Immunohistochemistry (PFA perfusion fixed frozen sections). Tissue was counterstained with Fluoro Nissl Green (green fluorescence).
  • Immunocytochemistry/ Immunofluorescence - Anti-Substance P antibody (ab10353)
    Immunocytochemistry/ Immunofluorescence - Anti-Substance P antibody (ab10353)
    Sustance P staining of trigeminal ganglia from P3-P5 rat pups.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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