Anti-Interferon alpha 1 antibody [F18] (ab7373)
Key features and details
- Rat monoclonal [F18] to Interferon alpha 1
- Reacts with: Mouse
- Isotype: IgG1
Overview
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Product name
Anti-Interferon alpha 1 antibody [F18]
See all Interferon alpha 1 primary antibodies -
Description
Rat monoclonal [F18] to Interferon alpha 1 -
Host species
Rat -
Specificity
This monoclonal antibody binds and neutralizes both natural and recombinant mouse alpha Interferon 1. This antibody does not cross-react with Human Interferon, Mouse Interferon beta or Mouse Interferon gamma. -
Species reactivity
Reacts with: Mouse
Does not react with: Human -
Positive control
- Plasmacytoid dendritic cells.
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General notes
With the availability of monoclonal antibodies directed against alpha Interferon, it is possible to interpret results obtained from crude materials containing both alpha and beta Interferon. The difficulties in studying in vitro and in vivo effects of "type 1" Interferons arise from the fact that both alpha and beta Interferons are produced in response to the same stimuli and also seem to act via the same receptor. These Interferon activities can only be distinguished from one another by use of specific neutralizing antibodies.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituents: 0.1% BSA, PBS -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
0.2 µm filtered antibody solution. -
Primary antibody notes
With the availability of monoclonal antibodies directed against alpha Interferon, it is possible to interpret results obtained from crude materials containing both alpha and beta Interferon. The difficulties in studying in vitro and in vivo effects of "type 1" Interferons arise from the fact that both alpha and beta Interferons are produced in response to the same stimuli and also seem to act via the same receptor. These Interferon activities can only be distinguished from one another by use of specific neutralizing antibodies. -
Clonality
Monoclonal -
Clone number
F18 -
Isotype
IgG1 -
Research areas
