Astana Biomed Group, an authorized Abcam distributor in Central Asia

Anti-Integrin beta 1d antibody [2B1] (ab8991)

Key features and details

  • Mouse monoclonal [2B1] to Integrin beta 1d
  • Suitable for: WB, IHC
  • Reacts with: Human
  • Isotype: IgG1

Overview

  • Product name

    Anti-Integrin beta 1d antibody [2B1]

  • Description

    Mouse monoclonal [2B1] to Integrin beta 1d

  • Host species

    Mouse

  • Specificity

    Recognizes specifically the cytoplasmic domain of integrin subunit beta 1D present in cardiac and skeletal muscle.

    A broad species reactivity is expected because of the conserved nature of the epitope.

  • Tested applications

    Suitable for: WB, IHCmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Synthetic peptide corresponding to Integrin beta 1d. The immunogen corresponds to the C-terminal 24 amino acids of integrin ß1D including an appending N-terminal cysteine (

    CQENPIYKS-PINNFKNPNYGRKAGL

    ) coupled to keyhole limpet hemocyanin.
    Database link: P05556
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Epitope

    Cytoplasmic domain, C-terminal. Isoform of the Integrin b1 subunit present in cardiac and skeletal muscle.

  • Positive control

    • WB: Human heart, tongue and skeletal muscle tissue lysates. IHC: Human myocardium.

  • General notes


    The integrins, finally, form a large family of glycosylated transmembrane proteins that act as dimers of an alpha and a beta subunit in interconnecting the cytoskeleton and the extracellular matrix.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...

  • Purity

    Protein G purified

  • Primary antibody notes

    The integrins, finally, form a large family of glycosylated transmembrane proteins that act as dimers of an alpha and a beta subunit in interconnecting the cytoskeleton and the extracellular matrix.

  • Clonality

    Monoclonal

  • Clone number

    2B1

  • Myeloma

    Sp2/0

  • Isotype

    IgG1

  • Light chain type

    kappa

  • Research areas

Images

  • Western blot - Anti-Integrin beta 1d antibody [2B1] (ab8991)
    Western blot - Anti-Integrin beta 1d antibody [2B1] (ab8991)

    Western blotting of beta1D integrin showing its muscle cell specific expression pattern.

  • Immunocytochemistry - Anti-Integrin beta 1d antibody [2B1] (ab8991)
    Immunocytochemistry - Anti-Integrin beta 1d antibody [2B1] (ab8991)

    Immunofluorescence staining of myocardium for beta1D integrin.

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