Anti-HoxC6 antibody (ab41587)
Key features and details
- Rabbit polyclonal to HoxC6
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-HoxC6 antibody
See all HoxC6 primary antibodies -
Description
Rabbit polyclonal to HoxC6This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
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Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Synthetic peptide corresponding to Human HoxC6 aa 100-200 conjugated to keyhole limpet haemocyanin.
(Peptide available asab41586)
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration
Concentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB HumanAll applications MouseRatApplication Abreviews Notes IHC-P (1) 1/50. Some customers have used this antibody successfully in IHC-P; however this is not a tested application for this antibody.WB Use at an assay dependent concentration. Predicted molecular weight: 26 kDa.Notes IHC-P
1/50. Some customers have used this antibody successfully in IHC-P; however this is not a tested application for this antibody.WB
Use at an assay dependent concentration. Predicted molecular weight: 26 kDa.Target
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Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. -
Sequence similarities
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 3223 Human
- Entrez Gene: 15425 Mouse
- Entrez Gene: 252885 Rat
- Omim: 142972 Human
- SwissProt: P09630 Human
- SwissProt: P10629 Mouse
- Unigene: 549040 Human
- Unigene: 4444 Mouse
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Alternative names
- CP25 antibody
- HHO.C8 antibody
- Homeo box 3C antibody
see all
Images
This Fast-Track antibody is not yet fully characterised. These images represent inconclusive preliminary data.-
Western blot - Anti-HoxC6 antibody (ab41587)All lanes : Anti-HoxC6 antibody (ab41587)
Lane 1 : Human ovary tissue lysate
Lane 2 : Human ovary tumor tissue lysate
Lane 3 : SK-N-BE cell lysate
Lane 4 : PC3 cell lysate
Lane 5 : MCF7 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP) at 1/50000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 26 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
Exposure time: 8 minutes
Protocols
Datasheets and documents
References (8)
ab41587 has been referenced in 8 publications.
- Yang P et al. Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma. Cancer Manag Res 11:8167-8179 (2019). PubMed: 31564976
- Zhang F et al. HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-ß/smad signaling pathway in cervical carcinoma cells. Cancer Cell Int 18:204 (2018). PubMed: 30559605
- Chang SL et al. HOXC6 Overexpression Is Associated With Ki-67 Expression and Poor Survival in NPC Patients. J Cancer 8:1647-1654 (2017). PubMed: 28775784
- Ji M et al. Silencing homeobox C6 inhibits colorectal cancer cell proliferation. Oncotarget 7:29216-27 (2016). IHC . PubMed: 27081081
- Jung H et al. Evolving Hox activity profiles govern diversity in locomotor systems. Dev Cell 29:171-87 (2014). PubMed: 24746670
- Ricard MJ & Gudas LJ Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells. J Biol Chem 288:28801-13 (2013). ICC/IF ; Mouse . PubMed: 23946489
- Mori M et al. Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells. PLoS Biol 10:e1001314 (2012). ICC/IF ; Human . PubMed: 22545021
- Vinagre T et al. Evidence for a myotomal Hox/Myf cascade governing nonautonomous control of rib specification within global vertebral domains. Dev Cell 18:655-61 (2010). ChIP ; Mouse . PubMed: 20412779
Images
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Western blot - Anti-HoxC6 antibody (ab41587)All lanes : Anti-HoxC6 antibody (ab41587)
Lane 1 : Human ovary tissue lysate
Lane 2 : Human ovary tumor tissue lysate
Lane 3 : SK-N-BE cell lysate
Lane 4 : PC3 cell lysate
Lane 5 : MCF7 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP) at 1/50000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 26 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
Exposure time: 8 minutes
