Astana Biomed Group, an authorized Abcam distributor in Central Asia

Anti-CPLX2 antibody (ab215046)

Key features and details

  • Sheep polyclonal to CPLX2
  • Suitable for: WB
  • Reacts with: Mouse
  • Isotype: IgG

Overview

Properties

  • Form

    Lyophilized:Reconstitute the antibody with 100 uL sterile PBS and the final concentration is 500 ug/mL. Reconstituted antibody can be aliquoted and stored frozen at

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    Constituent: 100% PBS
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Purification notes

    The IgG fraction of immunized serum was purified by antigen affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate-buffered saline (PBS).

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab215046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
WB
Mouse
All applications
Rat
Cow
Human
Torpedo
Application Abreviews Notes
WB
1/1000 - 1/2000. Predicted molecular weight: 15 kDa.
Notes
WB
1/1000 - 1/2000. Predicted molecular weight: 15 kDa.

Target

  • Function

    Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis.

  • Tissue specificity

    Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia.

  • Sequence similarities

    Belongs to the complexin/synaphin family.

  • Cellular localization

    Cytoplasm > cytosol. Enriched at synaptic-releasing sites in mature neurons.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • 921 L antibody
    • Complexin 2 antibody
    • Complexin II antibody
    • Complexin-2 antibody
    • Complexin2 antibody
    • ComplexinII antibody
    • CPLX 2 antibody
    • Cplx2 antibody
    • CPLX2_HUMAN antibody
    • CPX 2 antibody
    • CPX II antibody
    • CPXII antibody
    • Hfb1 antibody
    • Synaphin 1 antibody
    • Synaphin-1 antibody
    • Synaphin1 antibody
    see all

Images

  • Western blot - Anti-CPLX2 antibody (ab215046)
    Western blot - Anti-CPLX2 antibody (ab215046)
    Anti-CPLX2 antibody (ab215046) at 1/1000 dilution + mouse brain tissue lysate

    Predicted band size: 15 kDa

References (0)

Publishing research using ab215046? Please let us know so that we can cite the reference in this datasheet.

ab215046 has not yet been referenced specifically in any publications.

Images

  • Western blot - Anti-CPLX2 antibody (ab215046)
    Western blot - Anti-CPLX2 antibody (ab215046)
    Anti-CPLX2 antibody (ab215046) at 1/1000 dilution + mouse brain tissue lysate

    Predicted band size: 15 kDa

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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