Anti-CPLX2 antibody (ab215046)
Key features and details
- Sheep polyclonal to CPLX2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-CPLX2 antibody
See all CPLX2 primary antibodies -
Description
Sheep polyclonal to CPLX2 -
Host species
Sheep -
Tested Applications & Species
See all applications and species dataApplication Species WB Mouse
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Immunogen
Recombinant full length protein corresponding to Human CPLX2 aa 1-150. Expressed in E .coli.
Database link: Q6PUV4 -
Positive control
- Mouse brain tissue lysate.
Properties
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Form
Lyophilized:Reconstitute the antibody with 100 uL sterile PBS and the final concentration is 500 ug/mL. Reconstituted antibody can be aliquoted and stored frozen atStorage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.Storage buffer
Constituent: 100% PBS
Concentration information loading...Purity
Immunogen affinity purifiedPurification notes
The IgG fraction of immunized serum was purified by antigen affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate-buffered saline (PBS).Clonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Isotype control
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab215046 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB MouseAll applications RatCowHumanTorpedoApplication Abreviews Notes WB 1/1000 - 1/2000. Predicted molecular weight: 15 kDa.Notes WB
1/1000 - 1/2000. Predicted molecular weight: 15 kDa.Target
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Function
Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis. -
Tissue specificity
Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia. -
Sequence similarities
Belongs to the complexin/synaphin family. -
Cellular localization
Cytoplasm > cytosol. Enriched at synaptic-releasing sites in mature neurons. - Information by UniProt
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Database links
- Entrez Gene: 281711 Cow
- Entrez Gene: 10814 Human
- Entrez Gene: 12890 Mouse
- Entrez Gene: 116657 Rat
- Omim: 605033 Human
- SwissProt: P84088 Cow
- SwissProt: Q6PUV4 Human
- SwissProt: P84086 Mouse
see all -
Alternative names
- 921 L antibody
- Complexin 2 antibody
- Complexin II antibody
see all
Images
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Western blot - Anti-CPLX2 antibody (ab215046)Anti-CPLX2 antibody (ab215046) at 1/1000 dilution + mouse brain tissue lysate
Predicted band size: 15 kDa
Datasheets and documents
References (0)
ab215046 has not yet been referenced specifically in any publications.
Images
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Western blot - Anti-CPLX2 antibody (ab215046)Anti-CPLX2 antibody (ab215046) at 1/1000 dilution + mouse brain tissue lysate
Predicted band size: 15 kDa
