Anti-CES3/TGH antibody (ab215045)
Key features and details
- Sheep polyclonal to CES3/TGH
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-CES3/TGH antibody
See all CES3/TGH primary antibodies -
Description
Sheep polyclonal to CES3/TGH -
Host species
Sheep -
Tested Applications & Species
See all applications and species dataApplication Species WB Mouse
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Immunogen
Recombinant fragment corresponding to Mouse CES3/TGH aa 1 to the C-terminus. NS0-derived
Database link: Q8VCT4 -
Positive control
- Mouse lung tissue lysate.
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General notes
This product was previously labelled as CES3
Properties
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Form
Lyophilized:Reconstitute the antibody with 100 uL sterile PBS and the final concentration is 500 ug/mL. Reconstituted antibody can be aliquoted and stored frozen atStorage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.Storage buffer
Constituent: 100% PBS
Concentration information loading...Purity
Immunogen affinity purifiedPurification notes
The IgG fraction of immunized serum was purified by antigen affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate-buffered saline (PBS).Clonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab215045 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB MouseAll applications RatApplication Abreviews Notes WB 1/1000 - 1/2000. Predicted molecular weight: 62 kDa.Notes WB
1/1000 - 1/2000. Predicted molecular weight: 62 kDa.Target
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Function
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics. -
Tissue specificity
Expressed in liver, colon and small intestine. -
Sequence similarities
Belongs to the type-B carboxylesterase/lipase family. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Endoplasmic reticulum lumen. - Information by UniProt
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Database links
- Entrez Gene: 104158 Mouse
- Entrez Gene: 113902 Rat
- SwissProt: Q8VCT4 Mouse
- SwissProt: P16303 Rat
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Alternative names
- Carboxylesterase 3 antibody
- CES 3 antibody
- Ces3 antibody
see all
Images
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Western blot - Anti-CES3/TGH antibody (ab215045)Anti-CES3/TGH antibody (ab215045) at 1/1000 dilution + mouse lung tissue lysate
Predicted band size: 62 kDa
Datasheets and documents
References (0)
ab215045 has not yet been referenced specifically in any publications.
Images
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Western blot - Anti-CES3/TGH antibody (ab215045)Anti-CES3/TGH antibody (ab215045) at 1/1000 dilution + mouse lung tissue lysate
Predicted band size: 62 kDa