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Neuroscience Neurotransmission Receptors / Channels Potassium Channels

Amiodarone hydrochloride, Broad-spectrum ion channel blocker (ab141444)

Key features and details

  • Broad-spectrum ion channel blocker. Antiarrhythmic agent.
  • CAS Number: 19774-82-4
  • Purity: > 98%
  • Soluble in water to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Amiodarone hydrochloride, Broad-spectrum ion channel blocker
  • Description

    Broad-spectrum ion channel blocker. Antiarrhythmic agent.
  • Biological description

    Broad-spectrum ion channel blocker. Class III antiarrhythmic agent. Blocks late INa, ICa, IKr and IKs and increases QT. Shows beta blocker-like effects on the SA and AV nodes in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    19774-82-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2-Butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride
  • Molecular weight

    681.77
  • Molecular formula

    C25H29I2NO3.HCl
  • PubChem identifier

    441325
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl
  • Source

    Synthetic

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