AMI-5 (Eosin Y), PRMT inhibitor (ab144631)
Key features and details
- Non-selective PRMT inhibitor. Stain for cytoplasm.
- CAS Number: 17372-87-1
- Purity: > 90%
- Soluble in water to 3 mM and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
AMI-5 (Eosin Y), PRMT inhibitor -
Description
Non-selective PRMT inhibitor. Stain for cytoplasm. -
Alternative names
- Eosin Y
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Biological description
Non-selective PRMT inhibitor (IC50 values are 0.8 and 1.4 μM for Hmt1p and PRMT1 respectively). Stain for cytoplasm. Inhibits DOT1 and SET7. Decreases methylation of H3 histones at lysine 4. -
Purity
> 90% -
CAS Number
17372-87-1 -
Chemical structure
Properties
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Chemical name
2-(2,4,5,7-Tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate disodium salt -
Molecular weight
691.85 -
Molecular formula
C20H6Br4Na2O5 -
PubChem identifier
11048 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 3 mM and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C(=C1)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)Br)[O-])Br)Br)Br)C(=O)[O-].[Na+].[Na+] -
Source
Synthetic
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Research areas
