Akt Inhibitor (Akti-1/2), Akt1/2 kinase inhibitor (ab142088)
Key features and details
- Potent isozyme selective Akt1/2 kinase inhibitor
- CAS Number: 612847-09-3
- Purity: > 99%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Akt Inhibitor (Akti-1/2), Akt1/2 kinase inhibitor -
Description
Potent isozyme selective Akt1/2 kinase inhibitor -
Alternative names
- Akti-1/2
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Biological description
Potent isozyme selective Akt1/2 kinase inhibitor. (IC50 values are 58, 210 nM and 2.12 mM for Akt1, Akt2, and Akt3, respectively). No inhibition against pleckstrin homology (PH) domain-lacking Akts, PKA, PKC and SGK.
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Purity
> 99% -
CAS Number
612847-09-3 -
Chemical structure
Properties
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Chemical name
3-[1-[[4-(7-Phenyl-3H-imidazo[4,5-g]quinoxalin-6-yl)phenyl]methyl]piperidin-4-yl]-1H-benzimidazol-2-one -
Molecular weight
551.65 -
Molecular formula
C34H29N7O -
PubChem identifier
10196499 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=NC6=CC7=C(C=C6N=C5C8=CC=CC=C8)N=CN7 -
Source
Synthetic
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Research areas
