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Neuroscience Neurotransmission Receptors / Channels More Ion Channels

A-967079, TRPA1 receptor antagonist (ab144580)

Key features and details

  • Potent and selective TRPA1 receptor antagonist
  • CAS Number: 1170613-55-4
  • Purity: > 98%
  • Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    A-967079, TRPA1 receptor antagonist
  • Description

    Potent and selective TRPA1 receptor antagonist
  • Biological description

    Potent and selective TRPA1 receptor antagonist (IC50 = 67 nM). Displays no activity at other TRP channels. Analgesic agent. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    1170613-55-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1E,3E)-1-(4-Fluorophenyl)-2-methylpent-1-en-3-one oxime
  • Molecular weight

    207.25
  • Molecular formula

    C12H14FNO
  • PubChem identifier

    60150207
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCC(=NO)C(=CC1=CC=C(C=C1)F)C
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • More Ion Channels
    • Neuroscience
    • Sensory System
    • Somatosensory system
    • Nociception
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Ion Channels
    • TRP
    • Blockers

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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