5-Oxoete (5-Ketoeicosa-6E,8Z,11Z,14E-tetraenoic acid), Oxoeicosanoid (OXE) receptor agonist (ab141669)
Key features and details
- Oxoeicosanoid (OXE) receptor agonist. Chemoattractant for neutrophils and eosinophils.
- CAS Number: 106154-18-1
- Purity: > 95%
- Supplied in ethanol (50 µg/ml)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
5-Oxoete (5-Ketoeicosa-6E,8Z,11Z,14E-tetraenoic acid), Oxoeicosanoid (OXE) receptor agonist -
Description
Oxoeicosanoid (OXE) receptor agonist. Chemoattractant for neutrophils and eosinophils. -
Alternative names
- 5-KETE
- 5-Oxoete
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Biological description
Potent oxoeicosanoid (OXE) receptor agonist (EC50 = 0.33 nM). Potent chemoattractant for neutrophils and eosinophils. Induces a variety of rapid responses in neutrophils and eosinophils, including calcium mobilization, actin polymerization, CD11b expression, and L-selectin shedding. -
Purity
> 95% -
CAS Number
106154-18-1 -
Chemical structure
Properties
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Chemical name
(6E,8Z,11Z,14E)-5-Oxoicosa-6,8,11,14-tetraenoic acid -
Molecular weight
318.40 -
Molecular formula
C20H30O3 -
PubChem identifier
5353355 -
Storage instructions
Store at -80°C. -
Solubility overview
Supplied in ethanol (50 µg/ml) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCC=CCC=CCC=CC=CC(=O)CCCC(=O)O -
Source
Synthetic
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Research areas
