5-Hydroxytryptophol (Hydroxytryptophol), Endogenous serotonin structural analog (ab143639)
Key features and details
- Endogenous serotonin structural analog
- CAS Number: 154-02-9
- Purity: > 98%
- Soluble in water to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
5-Hydroxytryptophol (Hydroxytryptophol), Endogenous serotonin structural analog -
Description
Endogenous serotonin structural analog -
Alternative names
- Hydroxytryptophol
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Biological description
Endogenous serotonin structural analog. L-tryptophan metabolite. Competitively inhibits serotonin glucuronidation and UDP-glucuronosyltransferase (Ki values are 291 and 200 μM respectively). Blood-brain barrier permeable. Increases CNS synthesis of serotonin in vivo. Biomarker for ethanol consumption. Orally active. -
Purity
> 98% -
CAS Number
154-02-9 -
Chemical structure
Properties
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Chemical name
3-(2-Hydroxyethyl)-1H-indol-5-ol -
Molecular weight
177.20 -
Molecular formula
C10H11NO2 -
PubChem identifier
9061 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. -
Solubility overview
Soluble in water to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC2=C(C=C1O)C(=CN2)CCO -
Source
Synthetic
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Research areas
