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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

4-alpha-Phorbol-12-myristate-13-acetate, Negative control (ab143538)

Key features and details

  • Negative control for PMA
  • CAS Number: 63597-44-4
  • Purity: > 98%
  • Soluble in DMSO to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    4-alpha-Phorbol-12-myristate-13-acetate, Negative control
  • Description

    Negative control for PMA
  • Biological description

    Negative control for PMA. Opposes effects of PMA on PKC. Cell-permeable.
  • Purity

    > 98%
  • CAS Number

    63597-44-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(Acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester tetradecanoic acid
  • Molecular weight

    616.83
  • Molecular formula

    C36H56O8
  • PubChem identifier

    122634
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Nucleus
    • Other
    • Neuroscience
    • Neurotransmission
    • Intracellular Signaling
    • Phosphatases
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • More GPCR
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Signal Transduction
    • Second Messenger
    • Nucleotide Messenger
    • cGMP
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Estrogen
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Estrogen
    • Epigenetics and Nuclear Signaling
    • Cell cycle
    • Apoptosis
    • Nuclear
    • Cancer
    • Signal transduction
    • Nuclear signaling
    • Nuclear hormone receptors
    • Estrogen
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    • Pathways and Processes
    • Metabolic signaling pathways
    • Nucleotide metabolism
    • Molecular processes
    • Mitochondrial transcription
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Apoptosis
    • Cancer
    • Cell Death
    • Apoptosis
    • Nucleus
    • Other
    • Cancer
    • Cell Death
    • Apoptosis
    • Metabolism

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