3-Methylcrotonylglycine, amino acid metabolite (ab145925)
Key features and details
- Amino acid metabolite found in 3-methylcrotonylglycinuria
- CAS Number: 33008-07-0
- Purity: > 95%
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
3-Methylcrotonylglycine, amino acid metabolite -
Description
Amino acid metabolite found in 3-methylcrotonylglycinuria -
Alternative names
- 2-(3-methylbut-2-enoylamino)acetic
- 2-(3-methylbut-2-enoylamino)acetic acid
- 3-Methylcrotonyl Glycine
see all -
Biological description
Amino acid metabolite found in the metabolic disorder 3-methylcrotonylglycinuria. It is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. Increased levels of this metabolite are found in patients suffering from leucine catabolic disorders, such as 3-methylcrotonyl-CoA carboxylase deficiency and it is often considered a diagnostic marker of organic acidemias. Disrupts mitochondrial energy homeostasis and inhibits synaptic Na+, K+-ATPase activity in brain of young rats.
-
Purity
> 95% -
CAS Number
33008-07-0 -
Chemical structure
Properties
-
Chemical name
2-(3-Methylbut-2-enoylamino)acetic acid -
Molecular weight
157.17 -
Molecular formula
C7H11NO3 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
Source
Synthetic
