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25-Hydroxycholesterol, cholesterol metabolite (ab146145)

Key features and details

  • Biologically active cholesterol metabolite
  • CAS Number: 2140-46-7
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    25-Hydroxycholesterol, cholesterol metabolite
  • Description

    Biologically active cholesterol metabolite
  • Alternative names

    • 25-HC
    • 25-hydroxy-cholesterol
    • 25-OHC
    • Cholest-5-ene-3beta,25-diol
    • oxysterol
    see all
  • Biological description

    Cholesterol metabolite produced and secreted by macrophages in response to TLR activation. Regulates immune function and has a key role in the pathogenesis of atherosclerosis.

  • CAS Number

    2140-46-7
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    402.65
  • Molecular formula

    C27H46O2
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)(O)CCC[C@@H](C)[C@H]4CC[C@@H]3[C@]4(C)CC[C@H]2[C@H]3CC=C1C[C@@H](O)CC[C@@]12C
  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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