2-Hydroxyestradiol, Cytochrome P450 metabolite of estradiol (ab142519)
Key features and details
- Cytochrome P450 metabolite of estradiol
- CAS Number: 362-05-0
- This product is soluble in ethanol, DMSO, and DMF to about 20 mg/ml.
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-Hydroxyestradiol, Cytochrome P450 metabolite of estradiol -
Description
Cytochrome P450 metabolite of estradiol -
Biological description
Cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. Stimulates increase in β-adrenergic receptor density. Biological effects mediated by 2-methoxyestradiol after methylation of 2OHE by catechol-O-methyltransferase (COMT). Active in vivo and in vitro. -
CAS Number
362-05-0 -
Chemical structure
Properties
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Chemical name
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-2,3,17-triol
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Molecular weight
288.38 -
Molecular formula
C18H24O3 -
PubChem identifier
247304 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. The product can be stored for up to 12 months. -
Solubility overview
This product is soluble in ethanol, DMSO, and DMF to about 20 mg/ml. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)O)O -
Source
Synthetic
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Research areas
