10Panx, gap junction blocking peptide (ab269704)
Key features and details
- Gap junction blocking peptide
- CAS Number: 955091-53-9
Soluble in DMSO to 50 mM and 10 mM in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
10Panx, gap junction blocking peptide -
Description
Gap junction blocking peptide -
Biological description
Gap junction blocking peptide. Pannexin-1 imhibitory mimetic peptide. Blocks Pannexin-1 gap junctions. Inhibits dye uptake, ATP-mediated IL-1beta release and Caspase 1 activation mediated via macrophage P2X7 channels. Blocks NMDA secondary currents.
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CAS Number
955091-53-9 -
Chemical structure
Properties
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Molecular weight
1242.37 -
Molecular formula
C58H79N15O16 -
Sequence
WRQAAFVDSY -
PubChem identifier
44233736 -
Storage instructions
Shipped at Room Temperature. Store at -20°C long term. -
Solubility overview
Soluble in DMSO to 50 mM and 10 mM in water
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)N -
Source
Synthetic
Images
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Chemical Structure - 10Panx, gap junction blocking peptide (ab269704)
Chemical structure of 10Panx, gap junction blocking peptide, 955091-53-9